Almost lost in translation: integrated transcriptome and proteome analyses for early Arabidopsis flower development

Artículo

 

Te invitamos a leer el artículo "Almost lost in translation: integrated transcriptome and proteome analyses for early Arabidopsis flower development" publicado en Journal of Experimental Botany, ​a cargo del profesor investigador de la Unidad de Genómica Avanzada del Cinvestav Dr. Stefan de Folter, Profesor Investigador de la UGA.

Autores: Stefan de Folter  

  1. Unidad de Genómica Avanzada (UGA) del Centro de Investigación y Estudios Avanzados (Cinvestav)

Felicitamos al profesor que contibuyó en esta investigación por su arduo trabajo.

Summary:

Álvarez-Urdiola R, Matus JT, González-Miguel VM, Bernardo-Faura M, Riechmann JL. 2025. Chronology of transcriptome and proteome expression during early Arabidopsis fower development. Journal of Experimental Botany 76, 2743–2762 https://doi.org/10.1093/jxb/eraf005 Flower development is an intriguing biological phenomenon, and understanding the molecular pathways required is a popular research topic. Despite more than three decades of research, many topics remain unclear. Using shotgun proteomics (LC-MS/MS) and transcript profling (RNA-seq), Álvarez-Urdiola et al. (2025) investigated the chronology of the transcriptome and proteome expression during early fower development in Arabidopsis. One of the key fndings observed is an overall positive correlation between RNA and protein level changes, however RNA–protein pairs with anticorrelated gene expression changes were also observed. Furthermore, the generated transcriptome identifed additional differentially expressed genes during early fower development and, by using published ChIP-seq datasets, further direct target genes of the transcription factor APETALA1 were identifed.


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11/11/2024 01:41:23 p. m.